Designing distributed architecture

[Shanti]

Need suggestions on designing a distributed and failover Nagios  
monitoring infrastructure for ~1500 Linux RHEL hosts spread across 2  
datacenters and DMZ networks.
Reading through different archives, it appears DNX is the most  
preferred method for distribution/cluster setup and having a secondary  
Nagios server as a fail over option managed via Linux HA/DRBD.
What are some of the cons in following setup:

- Primary and secondary(failover) Nagios servers managed by Linux HA/ 
DRBD/cron etc. Have MySQL replication between them.
- Primary Nagios server performing active checks via N DNX worker  
nodes in both datacenters.
- Primary Nagios server monitoring DMZ hosts via NRPE (Custom regular  
expression for services).

Thanks
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