cfg file considerations for Nagios?

[RR]

I am making some Nagios 2.x config files that will be installed at
probably 100 locations for various administrators to monitor some
specific appliances on their network.

Is there anything that I need to take into consideration before
creating these cfg files if I am to make this completely compatible
with, say, GUI tools like Fruity or NagiosQL?

Some of the end users who might use these config files might be
wanting to use programs that make more tweaks configures easy, and I
want to make sure that my cfg files will be properly work with
whatever s/he installs.

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